2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID HYDRATE

2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID HYDRATE - Names and Identifiers

Name	2,4-Di(tert-butoxy)pyrimidin-5-ylboronic acid hydrate
Synonyms	AKOS BRN-0519 2,4-DI-TERT-BUTOXYPYRIMIDINE BORONIC ACID 2,6-di-tert-butoxypyrimidine-5-boronic acid 2,4-Di-tert-butoxypyrimidine-5-boronic acid 2,4-Ditert-butoxypyrimidin-5-ylboronic acid 2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID 2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID HYDRATE 2,4-Di(tert-butoxy)pyrimidin-5-ylboronic acid hydrate 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE 2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-YLBORONIC ACID HYDRATE
CAS	306935-93-3

2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID HYDRATE - Physico-chemical Properties

Molecular Formula	C12H21BN2O4
Molar Mass	268.12
Melting Point	>300°C
Solubility	Chloroform (Slightly), DMSO (Slightly)
Appearance	Solid
Color	Pale Yellow to Light Yellow
Storage Condition	2-8°C

2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID HYDRATE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves.
Hazard Class	IRRITANT

2,4-DI(TERT-BUTOXY)PYRIMIDINE-5-BORONIC ACID HYDRATE - Introduction

2,4-di (tert-butoxy)pyrimidin-5-ylboronic acid hydrate is an organic boron compound with the chemical formula C12H22BN3O3 · xH2O. Its general properties include a white crystalline solid, soluble in water and alcoholic solvents, and less soluble in organic solvents.

This compound is often used as a reagent and intermediate in organic synthesis. It can participate in esterification, aromatic substitution reaction and other reactions, and is used to prepare various compounds with pharmaceutical activity or biological activity.

The method for preparing 2,4-di (tert-butoxy)pyrimidin-5-ylboronic acid hydrate is generally obtained by reacting 2,4-di-tert-butoxypyrimidine with triphenyl boron, it is then reacted with hydrochloric acid to form the corresponding acid salt, which is finally obtained in the form of a hydrate by reaction with an alcohol.

Last Update：2024-04-09 02:00:45